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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDKN1B All Species: 13.64
Human Site: Y89 Identified Species: 37.5
UniProt: P46527 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46527 NP_004055.1 198 22073 Y89 G S L P E F Y Y R P P R P P K
Chimpanzee Pan troglodytes XP_522347 473 51257 F347 A S Q R K W N F D F Q N H K P
Rhesus Macaque Macaca mulatta XP_001085433 198 22067 Y89 G S L P E F Y Y R P P R A P K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P46414 197 22192 Y89 G S L P E F Y Y R P P R P P K
Rat Rattus norvegicus NP_113950 197 22121 Y89 G S L P E F Y Y R P P R P P K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_989587 198 22242 F89 G S S P D F Y F R Q P R L S K
Frog Xenopus laevis NP_001087934 141 15992 V35 R R S L F G P V D H E L L A R
Zebra Danio Brachydanio rerio NP_997957 179 20267 G73 T H T P R A D G R Y Q W E A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22197 184 21227 T78 T K V L T V R T T C S S L D I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 34.2 98.4 N.A. N.A. 87.8 87.3 N.A. N.A. 68.6 29.7 41.4 N.A. N.A. N.A. 22.2 N.A.
Protein Similarity: 100 35.9 98.9 N.A. N.A. 92.9 91.4 N.A. N.A. 78.7 44.4 58.5 N.A. N.A. N.A. 39.3 N.A.
P-Site Identity: 100 6.6 93.3 N.A. N.A. 100 100 N.A. N.A. 60 0 13.3 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 26.6 93.3 N.A. N.A. 100 100 N.A. N.A. 73.3 6.6 13.3 N.A. N.A. N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 0 12 0 0 0 0 0 0 12 23 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % C
% Asp: 0 0 0 0 12 0 12 0 23 0 0 0 0 12 0 % D
% Glu: 0 0 0 0 45 0 0 0 0 0 12 0 12 0 0 % E
% Phe: 0 0 0 0 12 56 0 23 0 12 0 0 0 0 0 % F
% Gly: 56 0 0 0 0 12 0 12 0 0 0 0 0 0 0 % G
% His: 0 12 0 0 0 0 0 0 0 12 0 0 12 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % I
% Lys: 0 12 0 0 12 0 0 0 0 0 0 0 0 12 56 % K
% Leu: 0 0 45 23 0 0 0 0 0 0 0 12 34 0 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 12 0 0 0 0 12 0 0 0 % N
% Pro: 0 0 0 67 0 0 12 0 0 45 56 0 34 45 12 % P
% Gln: 0 0 12 0 0 0 0 0 0 12 23 0 0 0 0 % Q
% Arg: 12 12 0 12 12 0 12 0 67 0 0 56 0 0 12 % R
% Ser: 0 67 23 0 0 0 0 0 0 0 12 12 0 12 0 % S
% Thr: 23 0 12 0 12 0 0 12 12 0 0 0 0 0 0 % T
% Val: 0 0 12 0 0 12 0 12 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 12 0 0 0 0 0 12 0 0 0 % W
% Tyr: 0 0 0 0 0 0 56 45 0 12 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _